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Successful Strategies to fight Obesity and Weight Gain
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Lysine and Herpes

      Lysine is one of the essential amino acids. It is a building block of protein that the body cannot synthesize from other materials and, therefore, must be obtained from our diet. Different proteins have different ratios of amino acids including essential and non-essential amino acids. Arginine is another essential amino acid that must be obtained from our diet.

Lysine for Herpes

      Lysine supplements and diets high in lysine and low in arginine have been used to discourage herpes outbreaks. Tissue culture studies have demonstrated that lysine inhibits viral replication. Analysis of the herpes simplex virons shows them to be rich in arginine and relatively lower in other essential amino acids including lysine. It appears that increasing the availability of lysine inhibits the utilization of arginine and slows virus replication. Experiments using Lysine supplements have shown that the intensity and frequency of outbreaks is reduced and quicker resolution of lesions is achieved.

      With many natural treatments, there is a lack of testing to definitively assess the safety and efficacy of the treatment for its intended purpose. In the case of Lysine and Herpes, there have been a number of clinical studies. If you read through the references cited below, you will see that there have been conflicting results. In one study, serum lysine levels were measured.(1) It was determined that when a person's serum lysine concentration exceeded 165 nmol/ml there was a corresponding significant decrease in recurrence rate. Conversely, the frequency rate increased significantly as concentration levels fell below 165 nmol/ml. These results suggest that prophylactic lysine may be useful in managing selected cases of recurrent herpes simplex labialis if serum lysine levels can be maintained at adequate concentrations. Those studies that did not report positive results may not have used a high enough dose of lysine to be effective or the participants may have had a diet high in arginine.

      It is also likely that arginine levels have an effect on results as well. If one wishes to suppress herpes virus growth with lysine supplements, it may be necessary to restrict arginine in the diet as well to keep the lysine to arginine ration in a favorable range. A list of foods with the arginine and lysine content and the arginine to lysine ratio is shown in the table below.

      It should also be noted that the studies that recorded positive results noted a reduction in the frequency of outbreaks and duration of outbreaks, not a complete suppression of outbreaks. This suggests that while lysine appears to be a useful therapy, best results may be obtained by combining it with additional therapies, either natural or orthodox.

      The dosage of lysine that has bee reported to keep herpes in remission and heal lesions varies from person to person. A typical dose to maintain remission has been reported to be approximately 500 mg. daily taken on an empty stomach between meals. The dosage required to induce healing has been reported to be between 1 and 6 grams between meals on an empty stomach.

      Given that arginine is an essential amino acid and has important roles in endocrine function, long term arginine restriction may not be the best practice. Other treatment options may be more effective and desirable.

Where to get Lysine

L-Lysine, 620 mg 100 capsules

L-Lysine, 620 mg 100 capsules

Lysine is an essential amino acid necessary for growth and to help maintain nitrogen balance in the body. (Essential amino acids cannot be made in the body and must be supplied by diet or supplements.) It may help promote proper nitrogen balance in the body and prevent glycosylation, the combining of a sugar and protein molecule accelerated by elevated levels of sugar in the blood.137,138

Lysine supplementation increases the absorption of calcium and may reduce its excretion.139 Some researchers believe that the disturbed balance of arginine and lysine may play a role in viral problems.140,141

Lysine works with other essential amino acids to maintain growth, lean body mass and the body’s store of nitrogen. In addition, dietary supplementation with the essential amino acid L-lysine has been shown to reduce anxiety in humans with low dietary intake of L-lysine. L-lysine, together with arginine, has been documented to normalize hormonal stress responses in humans with high trait anxiety.142

      To view the full list (64 products) of Lysine and Amino Acid Products from the Life Extension Foundation, Go Here.

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Ratio of Lysine to Arginine in Certain Foods

Transcribed and calculated using data from Agricultural Handbook, 1-23, U.S. Department of Agriculture.

Weight (gm) Lys (mg) Arg (mg) Ratio Lys/Arg
Margarine 14.1 9 3 3.000
Plain Yogurt 227 706 237 2.979
Fruit Yogurt, lowfat 227 810 272 2.978
Plain Yogurt, skim 227 1160 391 2.967
Plain Yogurt, lowfat 227 1060 359 2.953
Swiss Cheese 28 733 263 2.787
Gruyere Cheese 28 768 276 2.783
Edam Cheese 28 754 273 2.762
American Cheese Spread 28 427 155 2.755
Gouda Cheese 28 752 273 2.755
Whey, dry, sweet 7.5 77 28 2.750
Blue Cheese 28 526 202 2.604
Provolone Cheese 28 750 290 2.586
Papaya 454 76 30 2.533
Brie Cheese 28 525 208 2.524
Camermbert Cheese 28 501 199 2.518
Parmesan Cheese 28 937 373 2.512
Parmesan Cheese, grated 5 192 77 2.494
Gjetost Cheese 28 231 93 2.484
Goat Milk 244 708 291 2.433
Brick Cheese 28 602 248 2.427
Muenster Cheese 28 606 250 2.424
Beets 136 72 30 2.400
Limburger Cheese 28 475 198 2.399
Tilsit Cheese 28 578 241 2.398
Port du salut Cheese 28 563 235 2.396
Processed Swiss Cheese 28 696 293 2.375
Cream Cheese 28 192 81 2.370
Mozzarella Cheese, part s 28 699 295 2.369
Processed American Cheese 28 623 263 2.369
Mozzarella Cheese 28 559 236 2.369
Neufchatel Cheese 28 253 107 2.364
Butter 14.1 9 4 2.250
Colby Cheese 28 561 254 2.209
Monterey Jack Cheese 28 578 262 2.206
Cheshire Cheese 28 551 250 2.204
Cheddar Cheese 28 588 267 2.202
Buttermilk 245 679 309 2.197
Skim Milk 245 663 302 2.195
Half and Half Cream 242 568 259 2.193
Sherbet 193 171 78 2.192
Condensed Milk, sweetened 306 1920 876 2.192
Chocolate Milk 250 629 287 2.192
Nonfat Milk, dry 120 3440 1570 2.191
Lowfat Milk, 2% 244 644 294 2.190
Evaporated Milk 126 681 311 2.190
Ice Cream 133 381 174 2.190
Whole Milk 244 637 291 2.189
Whole Milk, dry 128 2670 1220 2.189
Nonfat Milk, dry, instant 68 1890 864 2.188
Ice Milk 131 409 187 2.187
Whipping Cream, heavy 238 387 177 2.186
Evaporated Milk, skim 128 763 349 2.186
Whipping Cream, light 239 411 188 2.186
Ice Cream, rich 148 327 150 2.180
Mango 300 85 39 2.179
Whipped Cream, pressurize 60 152 70 2.171
Apricot 114 103 48 2.146
Coffee Cream 15 32 15 2.133
Apple 150 17 8 2.125
Ricotta Cheese 246 3290 1550 2.123
Ricotta Cheese, part skim 246 3320 1570 2.115
Pear, dried 175 116 56 2.071
Eggnog 254 758 378 2.005
Applesauce, unsweetened 244 24 12 2.000
Crabapple, slices 110 28 14 2.000
Loquat 16 2 1 2.000
Apple, dried 64 37 19 1.947
Pear 180 23 12 1.917
Apricot, dried 35 89 49 1.816
Cottage Cheese, creamed 210 2120 1190 1.782
Cottage Cheese, Lowfat 2% 226 2510 1410 1.780
Cottage Cheese, dry 145 2020 1140 1.772
Fig, dried 189 228 131 1.740
Fig 65 19 11 1.727
Human Milk 246 168 105 1.600
Avocado 272 189 119 1.588
Salmon 85 1550 1000 1.550
Swordfish 85 1550 1000 1.550
Haddock 85 1480 961 1.540
Smelt 85 1380 897 1.538
Snapper 85 1600 1040 1.538
Pollock 85 1520 989 1.537
Eel 85 1440 938 1.535
Catfish 85 1420 925 1.535
Anchovy, in oit, drained 20 531 346 1.535
Whitefish 85 1490 971 1.535
Tuna, in water 165 4480 2920 1.534
Cod 85 1390 906 1.534
Flat fish, flounder and s 85 1470 959 1.533
Mackerel 85 1450 946 1.533
Shark 85 1640 1070 1.533
Carp 85 1390 907 1.533
Pike 85 1500 979 1.532
Herring 85 1400 914 1.532
Sardines, in oil, drained 24 542 354 1.531
Bass 85 1380 902 1.530
Perch 85 1450 948 1.530
Bluefish 85 1560 1020 1.529
Halibut 85 1620 1060 1.528
Tomato 123 41 27 1.519
Turnips 130 47 31 1.516
Tomato juice 243 54 36 1.500
Soybean sprouts 70 386 266 1.451
Canadian Style Bacon 454 7370 5100 1.445
Wild pheasant 371 7470 5240 1.426
Pork Spareribs 454 4730 3340 1.416
Tomato paste 262 282 200 1.410
Liver cheese 28 334 237 1.409
Chicken, dark meat, w/o s 109 1860 1320 1.409
Chicken, light meat w/o s 88 1730 1230 1.407
Chicken neck 79 298 212 1.406
Summer sausage 23 318 228 1.395
Pineapple 155 39 28 1.393
Pork leg 454 7550 5530 1.365
Pork loin chop 151 1950 1430 1.364
Pork Shoulder 454 7140 5240 1.363
Potato 150 190 140 1.357
Chicken breast 181 2500 1870 1.337
Cream of Mushroom soup 244 127 95 1.337
Turkey noodle soup 244 212 159 1.333
Celery 120 32 24 1.333
Chicken drumstick 110 1160 872 1.330
Potato, baking 202 283 214 1.322
Beef Flank steak 454 7270 5500 1.322
Chicken gumbo 244 161 122 1.320
Chicken noodle soup 241 219 166 1.319
Beef Round steak 454 7320 5550 1.319
Beef noodle soup 244 261 198 1.318
Vegetable w/beef soup 244 344 261 1.318
Cream of Asparagus soup 244 112 85 1.318
Porterhouse steak 454 6560 4980 1.317
Beef T-bone steak 454 6330 4810 1.316
Beef Sirloin steak 454 6880 5230 1.315
Knockwurst 68 634 482 1.315
Beef Rib roast 454 6050 4600 1.315
Beef Short ribs 454 5430 4130 1.315
Beef Chuck roast 454 6900 5250 1.314
Beef Tenderloin 454 6990 5320 1.314
Persimmon 200 55 42 1.310
Squash, summer 130 85 65 1.308
Chicken leg 231 2470 1890 1.307
Chicken, light meat 116 1920 1470 1.306
Ham, boneless 454 6750 5170 1.306
Chicken canned, boned 142 2500 1920 1.302
Turkey, dark meat 152 2620 2020 1.297
Cream of chicken soup 244 215 166 1.295
Chicken heart 6.1 79 61 1.295
Turkey, light meat 180 3540 2740 1.292
Bratwurst, ckd 85 910 706 1.289
Turkey, canned boned 142 3040 2360 1.288
Italian sausage, ckd 67 1020 792 1.288
Pork sausage 28 252 196 1.286
Wild quail 405 6660 5180 1.286
Chicken thigh 120 1310 1020 1.284
Chicken, dark meat 160 2150 1680 1.280
Goose, domesticated 320 4010 3150 1.273
Pork and beef sausage 13 141 111 1.270
Bologna, beef and pork 28 250 198 1.263
Peach, dried 130 151 120 1.258
Black bean soup 247 415 331 1.254
Bean w/ frankfurters soup 250 415 331 1.254
Peach 115 20 16 1.250
Corned Beef, brisket 454 5100 4100 1.244
Pastrami 28 375 302 1.242
Bologna, beef 28 254 205 1.239
Frankfurter, beef 45 389 314 1.239
Ground beef, regular 113 1560 1260 1.238
Cream of celery soup 244 73 59 1.237
Ground beef, lean 113 1670 1350 1.237
Chicken liver 32 35 352 1.236
Duck liver 44 624 505 1.236
Turkey liver 102 1540 1250 1.232
Mortadella 28 358 291 1.230
Goose liver 94 1160 943 1.230
Plum 5.5 90 74 1.216
Green beans 110 97 80 1.213
Chicken back 177 1090 900 1.211
Beef smoked, chopped 28 467 386 1.210
Pork Bacon 454 2900 2400 1.208
Beef, dried 28 673 557 1.208
Brotwurst 28 323 268 1.205
Polish sausage 28 315 262 1.202
Salami, hard 10 182 152 1.197
Bologna, pork 28 341 285 1.196
Chicken wing 90 698 585 1.193
Braunschweiger 28 258 217 1.189
Duck, domesticated 287 2610 2210 1.181
Lentil sprouts 77 548 470 1.166
Lettuce, romaine 56 58 50 1.160
Lettuce, iceberg 75 60 52 1.154
Caviar, black and red 16 293 254 1.154
Cauliflower 100 108 96 1.125
Vienna sausage 16 127 113 1.124
Liver 113 1570 1420 1.106
Guava 112 21 19 1.105
New England Clam Chowder 244 251 229 1.096
Cream of potato soup 244 83 76 1.092
Spinach 55 98 90 1.089
Kale 67 132 123 1.073
Chicken rice soup 241 251 234 1.073
Kielbasa 28 286 267 1.071
Frankfurter, beef and por 45 407 382 1.065
Whole Egg 50 410 388 1.057
Egg White 33 206 195 1.056
Whole Egg, dried 5 155 147 1.054
Watermelon 160 99 94 1.053
Cabbage, chinese 70 62 59 1.051
Corn 154 210 200 1.050
Sweet potato 130 105 100 1.050
Turnip greens 55 54 52 1.038
Abalone 85 1090 1060 1.028
Oysters 84 444 433 1.025
Clams 180 1720 1680 1.024
Scallops 85 1060 1040 1.019
Banana 175 55 54 1.019
Asparagus 134 194 192 1.010
Oat flakes 48 583 579 1.007
Mayonnaise 185 1400 1400 1.000
Vegetarian vegetable soup 241 99 99 1.000
Beet greens 38 20 20 1.000
Endive 50 32 32 1.000
Leeks 124 97 97 1.000
Pumpkin 245 96 96 1.000
Shrimp 85 1500 1510 0.993
Crab 85 1350 1360 0.993
pea soup w/ham 253 696 703 0.990
Lima beans, cooked 170 765 775 0.987
Egg Yolk 17 189 193 0.979
Okra 100 82 84 0.976
Broccoli 88 124 128 0.969
Chicken gizzard 37 465 484 0.961
Strawberries 149 37 39 0.949
Collards 186 140 72 0.931
Minestrone soup 241 183 198 0.924
Carrots 110 44 48 0.917
Dates 83 50 55 0.909
Peppers, sweet 100 38 42 0.905
Radish 45 16 18 0.889
Watercress 104 172 200 0.860
Swiss chard 36 36 42 0.857
Eggplant 82 42 50 0.840
Tomato soup 244 51 61 0.836
Cabbage, common 70 40 48 0.833
Wheat germ 180 1330 1790 0.743
Peas, green 146 463 625 0.741
Brussels sprouts 88 130 178 0.730
Tangerine 116 27 37 0.730
Orange 180 62 85 0.729
Onions, green 100 4 6 0.667
Mushrooms 70 48 72 0.667
Cucumber 104 22 36 0.611
Wheat granules 28.4 101 169 0.598
Corn grits 242 68 114 0.596
Snails 85 1250 2100 0.595
Wheat, shredded 23.6 79 133 0.594
Wheat flakes 33 101 171 0.591
Cream of wheat 251 98 166 0.590
Pistachios, shelled 128 1640 2790 0.588
Corn, puffed 28.4 65 112 0.580
Wheat, puffed 12 49 85 0.576
Squash, winter 205 902 1590 0.567
Bran flakes 47 177 314 0.564
Elderberries 145 38 68 0.559
Plantain 148 89 160 0.556
Oats, puffed 28.4 175 320 0.547
Oatmeal 234 78 147 0.531
Cashews 160 246 470 0.523
Chestnuts, fresh 160 246 470 0.523
Rice, puffed 14 38 73 0.521
Yams 200 89 191 0.466
Pumpkin seeds & squash 140 2530 5570 0.454
Garlic 3 8 19 0.421
Macadamia nuts 134 434 1200 0.362
Blackberries 145 17 49 0.347
Blueberries 145 17 49 0.347
Onions, mature 160 90 262 0.344
Grapes, slip skin 153 13 42 0.310
Grapes, adherent skin 160 24 78 0.308
Peanuts 144 1450 5050 0.287
Peanut butter 15 176 613 0.287
Coconut, shredded 80 118 437 0.270
Almonds 142 946 3540 0.267
Rutabaga 140 55 207 0.266
Pecans 108 315 1190 0.265
Sesame seeds 150 1240 4990 0.248
Hickory nuts 15 70 298 0.235
Brazil nuts 140 757 3350 0.226
Tahini 15 82 378 0.217
Grape juice 253 25 119 0.210
Tangerine juice 247 17 84 0.202
Pine nuts 28 256 1330 0.192
Orange juice 248 22 117 0.188
Hazelnuts 135 459 2480 0.185
Walnuts 100 466 2520 0.185

     





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