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N-Acetyl Cysteine, N-acetylcysteine

N-Acetyl Cysteine (NAC) is a metabolite of the sulfur-containing amino acid, Cysteine. Cysteine is found in high protein foods, N-Acetyl Cysteine is not. N-Acetyl Cysteine is produced within the human body. Cysteine plays a role in the sulfation cycle, acting as a sulfur donor in phase II detoxification and as a methyl donor in the conversion of homocysteine to methionine. Cysteine also helps synthesize glutathione, one of the body's most important natural antioxidants and detoxifiers. N-Acetyl-Cysteine is the acetylated form of L-Cysteine.

N-Acetyl Cysteine increases Glutathione Levels

N-Acetyl Cysteine is rapidly metabolized to intracellular glutathione. Glutathione acts as a powerful antioxidant in the body. Glutathione also detoxifies chemicals into less harmful compounds. N-Acetyl Cysteine also protects the body from acetaminophen toxicity and is used in hospitals for patients with acetaminophen poisoning. It has also been shown to be effective at treating liver failure from other causes as well.

N-Acetyl Cysteine Chelates Heavy Metals

Heavy metals like lead, mercury and arsenic are detoxified and removed from the body by N-Acetyl Cysteine . It also increases the excretion of zinc and other essential minerals when taken over an extended period. It is therefore necessary to supplement zinc, copper and other trace minerals when taking N-Acetyl Cysteine.

N-Acetyl Cysteine and the Immune System

Glutathione is known to aid in the transport of nutrients to lymphocytes and phagocytes, two major classes of immune cells, and to protect cell membranes. While purified glutathione is available as a dietary supplement, absorption is low, and N-Acetyl Cysteine is thought to be a better method of boosting cellular glutathione levels. N-Acetyl Cysteine is being investigated as a treatment for AIDS.

N-Acetyl Cysteine Breaks up Mucus

N-Acetyl Cysteine cleaves disulfide bonds by converting them to two sulfhydryl groups. This action results in the breakup of mucoproteins in lung mucus, reducing their chain lengths and thinning the mucus, improving conditions such as bronchitis and flu. Double-blind research has found that N-Acetyl Cysteine supplements improved symptoms and prevented recurrences in people with chronic bronchitis. N-Acetyl Cysteine at a dosage of 1,200 mg per day helps to prevent Influenza infection, reduces the symptoms of existing Influenza infection and reduces the duration of Influenza infections.

N-Acetyl Cysteine for Treating Psychiatric Disorders

N-Acetyl Cysteine is currently being investigated for the treatment of psychiatric disorders. These disorders include addiction, compulsive and grooming disorders, schizophrenia and bipolar disorder. N-acetylcysteine has shown promising results in populations with these disorders, including those in whom treatment efficacy has previously been limited.

N-Acetyl Cysteine and Cancer

N-Acetyl CysteineN-Acetyl Cysteine has been shown to reduce the proliferation of certain cells lining the colon and may reduce the risk of colon cancer in people with recurrent polyps in the colon. Its action as an antioxidant and a glutathione precursor may also contribute to a protective effect against cancer.

N-Acetyl Cysteine Side Effects and Safety

When taking N-acetyl cysteine it is recommended that two to three times as much vitamin C be taken at the same time. Failure to do so may result in more harm than good from taking this product because of the prolonged presence of the oxidized form of L-Cysteine. The vitamin C also helps keep the glutathione that is produced from the Cysteine in its reduced form so that it can continue acting as an antioxidant.

N-acetyl cysteine is likely safe for most adults when used in therapeutic dosage. In some individuals and under some conditions, It can cause nausea, vomiting, and diarrhea or constipation. Rarely, it can cause rashes, fever, headache, drowsiness, low blood pressure, and liver problems. If any of these symptoms are experienced, discontinue use and consult your physician.

There is insufficient information on using N-acetyl cysteine when pregnancy of breast feeding. Consult your pediatrician and use caution.

p N-acetyl Cysteine may act as a blood thinner. Do not use N-acetyl cysteine if taking anti-coagulant medications or before surgery.

N-acetyl Cysteine interacts with nitroglycerine increasing its potency. Avoid taking the two together.

N-Acetyl Cysteine Dosage

Typical dosage recommendations are in the range of 250-1500mg of NAC daily for the majority of therapeutic benefits. A common dosage is 600 mg. twice daily.

N-Acetyl Cysteine Supplements

Affiliate Disclosure: The website author will earn an affiliate commission if you purchase any products from any of the links on this page. There is no additional cost to the purchaser.

Here are some recommended N-acetyl Cysteine products.

N-Acetyl-L-Cysteine
N-Acetyl-L-Cysteine
Glutathione Cysteine Vitamin C
Glutathione Cysteine Vitamin C

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